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Collagen Biostimulators

Collagen biostimulators work beneath the skin to stimulate natural collagen production, restoring volume and improving skin firmness over time. They are ideal for facial rejuvenation, skin tightening, and long-term anti-aging benefits.

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Results

Gradual improvement over several weeks. Last up to 2 years. 


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Downtime

Minimal. Mild swelling or bruising may occur, subsiding within a few days.

Treatment Price

Sculptra 

฿27,500/vial (S$1,150)

Juvelook Volume

฿22,000/vial (S$920)

Juvelook 

฿15,000/vial (S$625)

Aftercare


  • Wash your face gently with water or a gentle cleanser if needed and avoid moisturiser for the first night after your treatment.

  • Limit heat exposure and strenuous exercise for the first one or two days.

  • Follow a gentle skincare routine and avoid acids and retinoids for the first 3 days.


*Sculptra Aftercare: 

  • Follow the 5-5-5 Rule: Massage the treated areas for 5 minutes, 5 times a day, for 5 days as advised by our doctors. Massaging is not required for juvelook treatments.

Aftercare

Wash your face gently with water or a gentle cleanser if needed and avoid moisturiser for the first night after your treatment.

Limit heat exposure and strenuous exercise for the first one or two days.

Follow a gentle skincare routine and avoid acids and retinoids for the first 3 days.

Avoid raw and fermented seafood for 1 week after the procedure.

Avoid alcohol for 1 week after the procedure.

Complete the aftercare medication prescribed by the doctor (if any).

Keep up with sunblock to maintain collagen production.

*Sculptra Aftercare:
Follow the 5-5-5 Rule: Massage the treated areas for 5 minutes, 5 times a day, for 5 days as advised by our doctors. Massaging is not required for juvelook treatments.

Product Information 

Sculptra®

Gradually restores volume by stimulating your body's natural collagen production, offering a natural-looking, long-lasting rejuvenation with minimal downtime.

 

Active Ingredient: Poly-L-lactic acid (PLLA)

Treats: Facial laxity, volume loss, sagging skin, deep folds.

Mechanism: Stimulates natural collagen synthesis to gradually restore volume and firmness.

Frequency: 2–3 sessions, 1 month apart; maintain every 1–2 years.

Benefits: Natural lift, firmer texture, long-lasting collagen renewal.

Technique: Injected in the deep dermis with a cannula for smooth, even lift.

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Gold Standard; long track record of safety, consistency and longest lasting results.

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Origin: USA

Onset: 3-5 days

Spread: Precise

Duration: 5-8 months

Allergan

Purest formulation with lower risks of forming botox resistance.

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Origin: Germany

Onset: 3-5 days

Spread: Precise

Duration: 3-6 months

Xeomin

High purity with fast onset. Precise distribution, ideal for fine lines.

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Origin: South Korea

Onset: 1-3 days

Spread: Narrow

Duration: 4-6 months

Aestox

Long-lasting; distributes evenly, great for treating a larger area like traptox.

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Origin: South Korea

Onset: 1-3days

Spread: Wide

Duration: 4-6 months

Nabota

Juvelook

Provides immediate and long term hydration on top of gradually increasing the collagen density and volume in the skin.

 

Active Ingredient: PDLLA + Hyaluronic Acid

Treats: Fine lines, enlarged pores, dullness, early skin laxity. Suitable for undereye volume restoration.
Mechanism: Combines collagen-stimulating PDLLA with HA for instant hydration and long-term firmness.

Frequency: 2–3 sessions, 1 month apart; maintain yearly.

Benefits: Refines pores, smooths skin, enhances glow and suppleness.

Techniques: 

  • Manual injections in the mid-dermis to refine texture and elasticity.

  • Cannula method to subtly restore undereye areas and nasolabial fold.

  • Microneedling injector to improve the appearance of pores and texture.

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Juvelook Volume

Provides progressive lift and structural support with long-term collagen regeneration, restoring facial contours naturally. Larger particle size of PDLLA works great at lifting the exterior planes of the face for natural results. Added hyaluronic acid gives much needed hydration to skin.
 

Active Ingredient (per vial): PDLLA + Hyaluronic Acid

Treats: Volume loss, sunken cheeks, temples, nasolabial folds, jawline laxity, early facial sagging. Not suitable for undereye areas.
Mechanism: Juvelook Volume contains double the PDLLA concentration and molecule size of Juvelook, allowing stronger collagen stimulation and volumising capacity. HA provides initial hydration and scaffold support, while PDLLA induces sustained collagen production to rebuild volume and firmness over time.

Frequency: 1–2 sessions, 6–8 weeks apart; maintenance every 12–18 months.

Benefits: Restores facial volume, increases skin thickness, improves firmness, delivers a natural lift without stiffness or overfilling.

Techniques: 

  • Cannula injections in deep dermis or subcutaneous planes for coherent volume. 

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All treatments at ReDerm Clinic are performed with Thai FDA-approved injectables and in full compliance with the highest safety and clinical standards.

  • Collagen biostimulators are injectable aesthetic treatments that stimulate the skin’s natural collagen production. Rather than simply filling lines, they improve skin firmness, elasticity, texture and overall skin quality gradually, resulting in natural-looking rejuvenation.

  • Sculptra: Made of poly-L-lactic acid (PLLA), primarily used for collagen stimulation and treating facial volume loss.

    Juvelook: A hybrid product combining Poly D-Lactic Acid (PDLLA) with hyaluronic acid, offering both immediate volume and hydration together with long-term collagen stimulation.

  • Yes, when administered by trained professionals. Proper technique minimizes risks like lumps or nodules.

  • No, unlike hyaluronic acid fillers, collagen biostimulators cannot be dissolved. It’s important to have a consultation to discuss your goals and expectations.

  • Ideal for individuals with moderate to severe volume loss or skin laxity.

    Not suitable for those who are pregnant and/or breastfeeding.

  • Dermal fillers provide immediate volume by physically filling space. Collagen biostimulators work biologically, activating fibroblasts to produce new collagen over time. Results are progressive, subtle and long-lasting, without an overfilled appearance.

  • At ReDerm Clinic, we offer doctor-selected, evidence-based collagen biostimulators:

    • Sculptra (PLLA) – deep collagen stimulation for overall firmness and structural support
       

    • Juvelook (PDLLA + HA) – improves pores, fine lines and skin texture
       

    • Juvelook Volume (PDLLA + HA) – collagen stimulation with additional volumising support
       

    Treatment choice is personalised based on skin condition, age and aesthetic goals.

  • Collagen biostimulators are suitable for:

    • Fine lines and early wrinkles

    • Enlarged pores and uneven texture

    • Dull or tired-looking skin

    • Early skin laxity

    • Loss of firmness and elasticity

    • Post-acne skin quality concerns

  • After injection, biostimulator particles trigger a controlled regenerative response in the skin. This activates fibroblasts to gradually produce new collagen, strengthening skin structure and improving firmness and resilience over time.

  • Early improvements in skin smoothness or hydration may appear within a few weeks. Visible collagen-related improvement typically develops from 4–6 weeks, with continued improvement over 2–3 months.

  • Results generally last 12–24 months, depending on the product used, treatment protocol, treatment area and individual collagen response. Maintenance treatments may be recommended.

  • Collagen biostimulators are usually performed as a course of treatment:
     

    • Most patients require 2–3 sessions

    • Sessions are spaced 4–6 weeks apart

    Your doctor will customise the protocol during consultation.

  • Discomfort is mild and well tolerated. Numbing cream is used together with numbing injections at no extra charge, and some products are mixed with local anaesthetic to enhance comfort.

  • Downtime is minimal. Temporary effects may include mild swelling, redness, small injection marks or bruising, which usually resolve within a few days. Most patients return to normal activities immediately.

  • Yes. They are commonly combined with:

    • Energy-based devices (RF, HIFU, lasers)

    • Skinboosters

    • Botox

    • Dermal Fillers

    • IV Drips

    Combination protocols often deliver optimal, long-term results.

  • You may be suitable if you:

    • Prefer natural, gradual skin rejuvenation

    • Have early signs of ageing or skin laxity

    • Want to improve overall skin quality

    • Do not want an overfilled or artificial look

    A medical consultation is essential to confirm suitability.

  • Collagen biostimulators may not be recommended if you are pregnant or breastfeeding, have active skin infection at the treatment area, or have certain autoimmune or connective tissue conditions.

  • No. Collagen biostimulators enhance skin quality and structure rather than creating instant bulk, resulting in subtle, natural and age-appropriate results.

  • ReDerm Clinic provides doctor-led collagen biostimulator treatments in Bangkok, trusted by many patients from Singapore. We focus on personalised planning, correct product selection, safety-driven techniques and long-term collagen health.

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