Gold Standard; long track record of safety, consistency and longest lasting results.
Origin: USA
Onset: 3-5 days
Spread: Precise
Duration: 5-8 months
Allergan
Purest formulation with lower risks of forming botox resistance.
Origin: Germany
Onset: 3-5 days
Spread: Precise
Duration: 3-6 months
Xeomin
High purity with fast onset. Precise distribution, ideal for fine lines.
Origin: South Korea
Onset: 1-3 days
Spread: Narrow
Duration: 4-6 months
Aestox
Long-lasting; distributes evenly, great for treating a larger area like traptox.
Origin: South Korea
Onset: 1-3days
Spread: Wide
Duration: 4-6 months
Nabota
Product Information
Therafill
A highly purified Atelocollagen (Type I) - 99.9% pure collagen with the allergy-triggering telopeptides removed, giving it a triple-helix structure that closely matches your own skin’s collagen. Premixed with lidocaine for comfort. Manufactured in South Korea under strict cold-chain “fresh collagen” standards.
Active Ingredient: Purified Atelocollagen (Type I) with premixed lidocaine
Treats: Fine lines, under-eye hollows and tear troughs, forehead and crow’s feet lines, shallow cheek folds, perioral lines, shallow acne scars, enlarged pores, dull or dehydrated skin
Mechanism: A two-step action - collagen fills and hydrates the skin immediately on injection, then stimulates fibroblasts over 2-4 weeks to build new collagen and elastin, repairing skin structure from within.
Frequency: 2-3 sessions, spaced 3-4 weeks apart; maintenance every 6-12 months
Benefits: Instant plumping plus long-term collagen renewal, bio-identical structure with low allergy risk, built-in comfort from premixed lidocaine, safe for delicate areas like the under-eyes.
Technique: Fine-needle or cannula injection into the dermis for smooth, even placement.
How it works
Step 1
Instant Fill & Hydration
Purified atelocollagen is injected directly into the skin, immediately plumping and hydrating treated areas.
Step 2
Rebuilds From Within
Over the next 2-4 weeks, the collagen matrix stimulates your own fibroblasts to produce new collagen and elastin, repairing skin structure from the inside out.
Step 3
Results That Build
Visible improvement continues for up to 12 weeks, with results lasting 6-12 months as your skin keeps renewing.
Treatment Area | Units |
|---|---|
Tear trough | 0.5 to 1cc each side |
Enhance cheeks | 1-2cc each side |
Nasalobial folds | 0.5 to 1cc each side |
Augment chin | 1cc |
Lips | 1cc |
Jaw | 1 to 2cc each side |
Temples | 0.5 to 1cc each side |
What's the difference?
Comparisons | Dermal Fillers | Collagen Biostimulators | Collagen Replacement (Therafill) |
|---|---|---|---|
Best for | Structural volume (cheeks, chin, lips) | Long-term collagen building | Skin quality, hydration, fine lines |
Duration | 6-18 months | 12-24 months | 6-12 months |
Onset of results | Immediate | 4-6 weeks | Immediate, continues building |
Mechanism | Adds volume directly | Triggers your own collagen production | Adds real collagen instantly, then stimulates more |
What it is
| Hyaluronic acid gel | PLLA / PDLLA biostimulator | Purified atelocollagen |
The amount of filler used are estimates.
For a more tailored solution, please make an appointment with our ReDerm doctors for a more accurate recommendation
Collagen Replacement
Collagen replacement delivers pure, bio-identical collagen directly into the skin, plumping and hydrating from the very first session, then continuing to rebuild your skin’s own collagen and elastin from within. Unlike biostimulators that take weeks to show results, collagen replacement injectables work instantly and proggressively, making it ideal for fine lines, hollows, and skin that has lost its natural bounce.
Aftercare
Avoid pressing, massaging, or applying strong pressure to treated areas for 24-48 hours.
Avoid alcohol and smoking for 1-3 days after the procedure.
Refrain from strenuous exercise for 3-5 days.
Avoid saunas, steam rooms, and direct sun exposure for 1-2 weeks.
Apply sunscreen diligently to protect your new collagen.
Complete the aftercare medication prescribed by the doctor (if any).
All treatments at ReDerm Clinic are performed with Thai FDA-approved injectables and in full compliance with the highest safety and clinical standards.
Collagen replacement uses Therafill, a purified Atelocollagen injectable, to add real collagen directly into the skin. Unlike biostimulators that only trigger your body to make collagen over time, Therafill plumps and hydrates the moment it’s injected, then continues to stimulate your own collagen and elastin production over the following weeks.
Sculptra and Juvelook are made of PLLA or PDLLA, which only stimulate your body to build collagen gradually, results take 4-6 weeks to appear. Therafill is collagen itself, so it plumps and hydrates instantly, then keeps building new collagen on top of that immediate effect.
Dermal fillers use hyaluronic acid to sculpt and add structural volume, ideal for reshaping the chin, cheeks, or lips. Therafill focuses on skin quality, firmness, elasticity, and hydration, making it better suited for those who want refreshed, healthy-looking skin rather than added contour.
Fine lines and superficial wrinkles, under-eye hollows and dark circles, forehead lines and crow’s feet, shallow cheek folds, perioral lines, shallow acne scars, enlarged pores, and dull or dehydrated skin.
Under-eyes and tear troughs, forehead and glabella, crow’s feet, cheeks, perioral area, and other areas where skin quality and firmness need a boost.
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Most patients need 2-3 sessions spaced 3-4 weeks apart. Results appear from the first session, build over 4-12 weeks, and last 6-12 months depending on your skin’s metabolism and lifestyle.
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Therafill comes premixed with lidocaine, and numbing cream can be applied beforehand, so discomfort is minimal.
Downtime is minimal. Mild swelling, redness, or small injection bumps may appear and typically resolve within 1-3 days.
Yes. Its purified, telopeptide-removed structure closely resembles your own collagen, giving it a low allergy risk and excellent biocompatibility. As with any injectable, a consultation with our doctors is essential to confirm suitability.
Not recommended for those who are pregnant or breastfeeding, have a known allergy to collagen or lidocaine, active skin infection at the treatment area, or certain autoimmune conditions. Consult with our doctors if in doubt.
Yes. It pairs well with Botox, dermal fillers, energy-based devices, and skinboosters. Consult with our doctors for a tailored treatment plan.
ReDerm Clinic offers doctor-led Therafill treatments in Bangkok, trusted by patients from Singapore. We focus on personalised planning, correct product selection, and safety-driven techniques for natural, long-lasting results.